Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

ISM2 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 145501 isthmin 2 chr14 - 77964710 - 77970210 77965210 Transcription Factor Binding Sites   Download all TFBS in the ISM2 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints FOXB1_forkhead_DBD_dimeric_18_1 SELEX + 77968804 77968821 3.0E-06 TTTATAAATGTTGGTTTT 18 FOXB1_forkhead_DBD_dimeric_18_1 SELEX - 77968804 77968821 4.0E-06 AAAACCAACATTTATAAA 18 FOXO4_forkhead_DBD_dimeric_14_1 SELEX + 77968758 77968771 6.0E-06 AGAAACAAGTTTGC 14 SPIC_ETS_full_monomeric_14_1 SELEX + 77961803 77961816 6.0E-06 TAAAATAGAAAGTA 14 EMX2_homeodomain_DBD_dimeric_14_1 SELEX + 77961845 77961858 5.0E-06 AATTTAGTTAATTT 14 EMX2_homeodomain_DBD_dimeric_14_1 SELEX - 77961845 77961858 2.0E-06 AAATTAACTAAATT 14 RARA_nuclearreceptor_full_dimeric_18_1 SELEX - 77965391 77965408 3.0E-06 CAGGGTCAAGACGGGTCG 18 MEF2D_MADS_DBD_dimeric_12_1 SELEX + 77961769 77961780 1.0E-06 GCTAAAAATAAT 12 NR2E1_nuclearreceptor_full_monomeric_9_1 SELEX + 77964741 77964749 7.0E-06 AGAAGTCAA 9 LHX2_homeodomain_DBD_dimeric_15_1 SELEX + 77961844 77961858 6.0E-06 CAATTTAGTTAATTT 15 LHX2_homeodomain_DBD_dimeric_15_1 SELEX - 77961844 77961858 7.0E-06 AAATTAACTAAATTG 15 LHX2_homeodomain_DBD_dimeric_15_1 SELEX - 77961849 77961863 9.0E-06 TAATAAAATTAACTA 15 Foxj3_forkhead_DBD_putatively-multimeric_11_1 SELEX - 77968581 77968591 5.0E-06 ATGTACACAAT 11 RARG_nuclearreceptor_full_dimeric_17_1 SELEX - 77965391 77965407 4.0E-06 AGGGTCAAGACGGGTCG 17 Rarb_nuclearreceptor_DBD_dimeric_18_1 SELEX - 77965391 77965408 8.0E-06 CAGGGTCAAGACGGGTCG 18 MEF2A_MADS_DBD_dimeric_12_1 SELEX + 77961769 77961780 1.0E-06 GCTAAAAATAAT 12 IRF7_IRF_DBD_trimeric_17_1 SELEX + 77968677 77968693 3.0E-06 AAAACAAAATTCTTGTC 17 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 77961771 77961784 3.0E-06 TAAAAATAATTACA 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX - 77961771 77961784 1.0E-05 TGTAATTATTTTTA 14 FOXD2_forkhead_DBD_dimeric_14_1 SELEX + 77968806 77968819 8.0E-06 TATAAATGTTGGTT 14 TCF7L1_HMG_full_monomeric_12_1 SELEX - 77965419 77965430 9.0E-06 CCAGATCAAAGA 12 LEF1_HMG_DBD_monomeric_15_1 SELEX - 77965416 77965430 8.0E-06 CCAGATCAAAGAGAG 15 MEF2B_MADS_full_dimeric_12_1 SELEX + 77961769 77961780 1.0E-06 GCTAAAAATAAT 12 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 77961771 77961784 7.0E-06 TAAAAATAATTACA 14 FOXD3_forkhead_DBD_dimeric_14_1 SELEX + 77968806 77968819 8.0E-06 TATAAATGTTGGTT 14 RARG_nuclearreceptor_DBD_dimeric_17_2 SELEX - 77965391 77965407 5.0E-06 AGGGTCAAGACGGGTCG 17 MEF2A_MA0052.1 JASPAR - 77961770 77961779 2.0E-06 TTATTTTTAG 10 FOXI1_MA0042.1 JASPAR + 77965674 77965685 7.0E-06 AGATGTTTGGTT 12 NFIX_NFI_full_monomeric_9_2 SELEX + 77961839 77961847 8.0E-06 AATGCCAAT 9 MEOX2_homeodomain_DBD_monomeric_10_1 SELEX - 77961775 77961784 7.0E-06 TGTAATTATT 10 FOXC1_forkhead_DBD_dimeric_14_1 SELEX + 77961771 77961784 6.0E-06 TAAAAATAATTACA 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 77961771 77961784 9.0E-06 TGTAATTATTTTTA 14 FOXC1_forkhead_DBD_dimeric_14_1 SELEX - 77968806 77968819 9.0E-06 AACCAACATTTATA 14 Lhx3_MA0135.1 JASPAR - 77961846 77961858 1.0E-06 AAATTAACTAAAT 13 PBX1_MA0070.1 JASPAR - 77968729 77968740 6.0E-06 AAGTCAATCAAA 12 RARG_nuclearreceptor_DBD_dimeric_17_1 SELEX - 77965391 77965407 5.0E-06 AGGGTCAAGACGGGTCG 17 PRDM1_C2H2_full_monomeric-or-dimeric_15_1 SELEX + 77961803 77961817 9.0E-06 TAAAATAGAAAGTAT 15 FOXC2_forkhead_DBD_dimeric_14_1 SELEX + 77961771 77961784 2.0E-06 TAAAAATAATTACA 14 FOXC2_forkhead_DBD_dimeric_14_1 SELEX - 77961771 77961784 3.0E-06 TGTAATTATTTTTA 14 ZNF282_C2H2_DBD_monomeric_17_1 SELEX - 77961740 77961756 6.0E-06 TCTTCCCCTAACAAGAA 17 SPDEF_ETS_full_putative-multimer_16_1 SELEX + 77961792 77961807 2.0E-06 GCAGTAAGTACTAAAA 16 TEAD1_TEA_full_dimeric_17_1 SELEX + 77968588 77968604 9.0E-06 ACATAGCGTACATGCTT 17 EMX1_homeodomain_DBD_dimeric_14_1 SELEX + 77961845 77961858 8.0E-06 AATTTAGTTAATTT 14 EMX1_homeodomain_DBD_dimeric_14_1 SELEX - 77961845 77961858 4.0E-06 AAATTAACTAAATT 14 Sox3_HMG_DBD_dimeric_17_1 SELEX + 77961835 77961851 7.0E-06 AAACAATGCCAATTTAG 17 NFIA_NFI_full_monomeric_10_1 SELEX - 77961756 77961765 5.0E-06 TTTGCCAAAT 10 V_FOXP1_01_M00987 TRANSFAC + 77968805 77968824 7.0E-06 TTATAAATGTTGGTTTTTCA 20 V_CEBPG_Q6_M00622 TRANSFAC + 77968800 77968812 2.0E-06 CTGATTTATAAAT 13 V_TST1_02_M01316 TRANSFAC - 77961845 77961861 5.0E-06 ATAAAATTAACTAAATT 17 V_TCF3_01_M01594 TRANSFAC - 77961781 77961793 2.0E-06 GCTTTGTATTGTA 13 V_LEF1_04_M02774 TRANSFAC + 77965415 77965431 3.0E-06 GCTCTCTTTGATCTGGC 17 V_LEF1_04_M02774 TRANSFAC + 77968630 77968646 7.0E-06 ATTGCCTTTGAACTACT 17 V_CDX2_Q5_01_M01659 TRANSFAC + 77968804 77968814 7.0E-06 TTTATAAATGT 11 V_TCFE2A_04_M02927 TRANSFAC + 77965668 77965684 8.0E-06 CCGGGCAGATGTTTGGT 17 V_SOX40_04_M02908 TRANSFAC + 77961775 77961790 8.0E-06 AATAATTACAATACAA 16 V_SRY_07_M02813 TRANSFAC + 77961775 77961790 4.0E-06 AATAATTACAATACAA 16 V_SRY_07_M02813 TRANSFAC - 77961775 77961790 3.0E-06 TTGTATTGTAATTATT 16 V_HNF1_02_M01379 TRANSFAC + 77968658 77968674 6.0E-06 TGTAGGTTAACTGGTAG 17 V_CEBP_Q3_M00770 TRANSFAC + 77961754 77961765 2.0E-06 AGATTTGGCAAA 12 V_DLX3_01_M01400 TRANSFAC + 77961771 77961787 0.0E+00 TAAAAATAATTACAATA 17 V_HMGIY_Q3_M01010 TRANSFAC - 77961772 77961786 3.0E-06 ATTGTAATTATTTTT 15 V_MMEF2_Q6_M00405 TRANSFAC + 77961766 77961781 1.0E-05 CATGCTAAAAATAATT 16 V_TCF4_Q5_01_M02033 TRANSFAC - 77965417 77965426 7.0E-06 ATCAAAGAGA 10 V_PROP1_01_M01294 TRANSFAC - 77961772 77961782 6.0E-06 TAATTATTTTT 11 V_PROP1_01_M01294 TRANSFAC + 77961777 77961787 8.0E-06 TAATTACAATA 11 V_MEF2_02_M00231 TRANSFAC + 77961763 77961784 3.0E-06 AAACATGCTAAAAATAATTACA 22 V_IRF_Q6_01_M00972 TRANSFAC + 77961804 77961814 8.0E-06 AAAATAGAAAG 11 V_CEBP_01_M00159 TRANSFAC + 77965677 77965689 6.0E-06 TGTTTGGTTATGC 13 V_FOXO3A_Q1_M01137 TRANSFAC + 77961771 77961782 5.0E-06 TAAAAATAATTA 12 V_FOXO3A_Q1_M01137 TRANSFAC + 77968675 77968686 9.0E-06 CAAAAACAAAAT 12 V_NKX61_03_M01489 TRANSFAC + 77961771 77961787 4.0E-06 TAAAAATAATTACAATA 17 V_DLX2_01_M01468 TRANSFAC + 77961773 77961788 1.0E-06 AAAATAATTACAATAC 16 V_HOXC6_01_M01406 TRANSFAC - 77961771 77961787 1.0E-05 TATTGTAATTATTTTTA 17 V_HOXC6_01_M01406 TRANSFAC + 77961772 77961788 6.0E-06 AAAAATAATTACAATAC 17 V_LHX3A_01_M00510 TRANSFAC - 77961848 77961857 9.0E-06 AATTAACTAA 10 V_SOX21_03_M02803 TRANSFAC + 77961775 77961790 4.0E-06 AATAATTACAATACAA 16 V_SOX21_03_M02803 TRANSFAC - 77961775 77961790 1.0E-06 TTGTATTGTAATTATT 16 V_CART1_03_M01453 TRANSFAC + 77961844 77961860 9.0E-06 CAATTTAGTTAATTTTA 17 V_NKX62_Q2_M00489 TRANSFAC + 77961773 77961784 2.0E-06 AAAATAATTACA 12 V_MEF2A_Q6_M02024 TRANSFAC - 77961769 77961778 1.0E-06 TATTTTTAGC 10 V_BARBIE_01_M00238 TRANSFAC + 77961785 77961799 9.0E-06 ATACAAAGCAGTAAG 15 V_HMGA2_01_M01300 TRANSFAC + 77968794 77968808 2.0E-06 ATATTCCTGATTTAT 15 V_ELF4_04_M02850 TRANSFAC + 77961767 77961783 9.0E-06 ATGCTAAAAATAATTAC 17 V_ELF4_04_M02850 TRANSFAC + 77961769 77961785 1.0E-05 GCTAAAAATAATTACAA 17 V_HMBOX1_01_M01456 TRANSFAC + 77961843 77961859 1.0E-06 CCAATTTAGTTAATTTT 17 V_TCF3_04_M02816 TRANSFAC - 77968630 77968646 3.0E-06 AGTAGTTCAAAGGCAAT 17 V_HOXA6_01_M01392 TRANSFAC + 77961773 77961788 1.0E-06 AAAATAATTACAATAC 16 V_IPF1_Q4_M00436 TRANSFAC - 77968780 77968791 3.0E-06 AAATTAATGTCC 12 V_SOX8_04_M02912 TRANSFAC + 77961814 77961827 9.0E-06 GTATTCATGCCAAG 14 V_NFAT_Q6_M00302 TRANSFAC + 77968567 77968578 3.0E-06 CAGTGGAAAACT 12 V_MRF2_01_M00454 TRANSFAC + 77961778 77961791 0.0E+00 AATTACAATACAAA 14 V_RSRFC4_Q2_M00407 TRANSFAC + 77961767 77961783 0.0E+00 ATGCTAAAAATAATTAC 17 V_AMEF2_Q6_M00403 TRANSFAC + 77961766 77961783 1.0E-06 CATGCTAAAAATAATTAC 18 V_AMEF2_Q6_M00403 TRANSFAC - 77961848 77961865 1.0E-06 GATAATAAAATTAACTAA 18 V_HOXB6_01_M01460 TRANSFAC + 77961771 77961786 4.0E-06 TAAAAATAATTACAAT 16 V_LXR_DR4_Q3_M00766 TRANSFAC + 77965391 77965406 4.0E-06 CGACCCGTCTTGACCC 16 V_SOX_Q6_M01014 TRANSFAC + 77965418 77965430 5.0E-06 CTCTTTGATCTGG 13 V_MEF2_03_M00232 TRANSFAC + 77961763 77961784 0.0E+00 AAACATGCTAAAAATAATTACA 22 V_OCT1_08_M01354 TRANSFAC - 77961849 77961864 8.0E-06 ATAATAAAATTAACTA 16 V_MEF2_04_M00233 TRANSFAC + 77961763 77961784 5.0E-06 AAACATGCTAAAAATAATTACA 22 V_MEF2_04_M00233 TRANSFAC + 77968667 77968688 2.0E-06 ACTGGTAGCAAAAACAAAATTC 22 V_TCF7_03_M02817 TRANSFAC - 77965415 77965431 9.0E-06 GCCAGATCAAAGAGAGC 17 V_TCF7_03_M02817 TRANSFAC - 77968630 77968646 3.0E-06 AGTAGTTCAAAGGCAAT 17 V_PBX1_05_M01967 TRANSFAC + 77968729 77968742 7.0E-06 TTTGATTGACTTCC 14 V_HB24_01_M01399 TRANSFAC + 77961770 77961784 1.0E-05 CTAAAAATAATTACA 15 V_ISGF3G_03_M02771 TRANSFAC - 77968785 77968799 7.0E-06 GAATATCGAAATTAA 15 V_NKX63_01_M01470 TRANSFAC + 77961771 77961787 9.0E-06 TAAAAATAATTACAATA 17 V_NKX23_01_M01457 TRANSFAC - 77961793 77961808 7.0E-06 ATTTTAGTACTTACTG 16 V_FOXO1_Q5_M01216 TRANSFAC + 77968676 77968684 1.0E-06 AAAAACAAA 9 V_GATA4_Q3_M00632 TRANSFAC - 77965417 77965428 4.0E-06 AGATCAAAGAGA 12 V_GR_Q6_02_M01836 TRANSFAC + 77968706 77968718 4.0E-06 CAATCTGTCCTGT 13 V_DLX7_01_M01486 TRANSFAC + 77961771 77961787 1.0E-06 TAAAAATAATTACAATA 17 V_HOXB7_01_M01396 TRANSFAC - 77961771 77961786 9.0E-06 ATTGTAATTATTTTTA 16 V_HOXA7_02_M01336 TRANSFAC + 77961772 77961788 7.0E-06 AAAAATAATTACAATAC 17 V_BRN4_01_M01473 TRANSFAC - 77961845 77961861 4.0E-06 ATAAAATTAACTAAATT 17 V_BRN4_01_M01473 TRANSFAC + 77961846 77961862 8.0E-06 ATTTAGTTAATTTTATT 17 V_HOXB8_01_M01451 TRANSFAC - 77961772 77961787 1.0E-05 TATTGTAATTATTTTT 16 V_IPF1_05_M01255 TRANSFAC + 77968780 77968791 9.0E-06 GGACATTAATTT 12 V_OSR2_04_M02889 TRANSFAC - 77968664 77968679 7.0E-06 TTTTGCTACCAGTTAA 16 V_CACBINDINGPROTEIN_Q6_M00720 TRANSFAC - 77965357 77965365 8.0E-06 GAGGGTGGG 9 V_NKX3A_02_M01383 TRANSFAC + 77961793 77961809 3.0E-06 CAGTAAGTACTAAAATA 17 V_IPF1_01_M01233 TRANSFAC + 77961774 77961783 1.0E-05 AAATAATTAC 10 V_TCF1_06_M02815 TRANSFAC - 77961845 77961861 2.0E-06 ATAAAATTAACTAAATT 17 V_DMRT7_01_M01151 TRANSFAC - 77961772 77961785 6.0E-06 TTGTAATTATTTTT 14 V_MSX1_02_M01412 TRANSFAC + 77961771 77961786 8.0E-06 TAAAAATAATTACAAT 16 V_LMX1B_01_M01363 TRANSFAC + 77961843 77961859 5.0E-06 CCAATTTAGTTAATTTT 17 V_LMX1B_01_M01363 TRANSFAC - 77961844 77961860 6.0E-06 TAAAATTAACTAAATTG 17 V_NRSF_01_M00256 TRANSFAC + 77965072 77965092 6.0E-06 TCCAGCAGCGCCGCCAGCAGC 21 V_TCF4_Q5_M00671 TRANSFAC + 77968634 77968641 1.0E-05 CCTTTGAA 8 V_PBX1_02_M00124 TRANSFAC - 77968727 77968741 2.0E-06 GAAGTCAATCAAACT 15 V_RSRFC4_01_M00026 TRANSFAC - 77961767 77961782 1.0E-06 TAATTATTTTTAGCAT 16 V_BBX_03_M02739 TRANSFAC - 77961849 77961863 6.0E-06 TAATAAAATTAACTA 15 V_R_01_M00273 TRANSFAC - 77965163 77965183 7.0E-06 GCGGCCGCGTGCAGAGGTGCA 21 V_OCT1_07_M00248 TRANSFAC - 77961778 77961789 2.0E-06 TGTATTGTAATT 12 V_IRF1_Q6_01_M01881 TRANSFAC - 77961803 77961816 5.0E-06 TACTTTCTATTTTA 14 V_SOX8_03_M02808 TRANSFAC - 77961776 77961792 8.0E-06 CTTTGTATTGTAATTAT 17 V_SRF_06_M02916 TRANSFAC + 77968546 77968562 3.0E-06 CTGTAGAAAAAAACTGT 17 V_SRF_06_M02916 TRANSFAC + 77968671 77968687 9.0E-06 GTAGCAAAAACAAAATT 17 V_DLX3_02_M02051 TRANSFAC + 77961776 77961783 5.0E-06 ATAATTAC 8 V_IPF1_Q4_01_M01013 TRANSFAC + 77968778 77968792 8.0E-06 TTGGACATTAATTTC 15 V_FOXO1_01_M00473 TRANSFAC + 77968675 77968684 4.0E-06 CAAAAACAAA 10 V_SOX2_Q6_M01272 TRANSFAC - 77968675 77968690 8.0E-06 AAGAATTTTGTTTTTG 16 V_MOX1_01_M01443 TRANSFAC + 77961773 77961788 7.0E-06 AAAATAATTACAATAC 16 V_PAX4_02_M00377 TRANSFAC + 77961774 77961784 2.0E-06 AAATAATTACA 11 V_MEF2_01_M00006 TRANSFAC + 77961768 77961783 2.0E-06 TGCTAAAAATAATTAC 16 V_HOXD3_01_M01338 TRANSFAC + 77961771 77961786 9.0E-06 TAAAAATAATTACAAT 16 V_FREAC4_01_M00292 TRANSFAC - 77968579 77968594 9.0E-06 GCTATGTACACAATGC 16 V_LHX4_01_M01421 TRANSFAC - 77961771 77961787 2.0E-06 TATTGTAATTATTTTTA 17 V_FOXO4_01_M00472 TRANSFAC + 77968676 77968686 1.0E-05 AAAAACAAAAT 11 V_HMEF2_Q6_M00406 TRANSFAC + 77961768 77961783 2.0E-06 TGCTAAAAATAATTAC 16 V_HMEF2_Q6_M00406 TRANSFAC - 77961848 77961863 4.0E-06 TAATAAAATTAACTAA 16 V_HOXA10_01_M01464 TRANSFAC - 77961771 77961786 8.0E-06 ATTGTAATTATTTTTA 16 V_CMAF_01_M01070 TRANSFAC + 77968793 77968811 9.0E-06 GATATTCCTGATTTATAAA 19 V_IPF1_04_M01236 TRANSFAC + 77968783 77968792 1.0E-05 CATTAATTTC 10 V_TCF3_05_M02920 TRANSFAC + 77961767 77961781 3.0E-06 ATGCTAAAAATAATT 15 V_TCF3_05_M02920 TRANSFAC + 77968672 77968686 6.0E-06 TAGCAAAAACAAAAT 15 V_SOX14_03_M02798 TRANSFAC + 77961769 77961784 9.0E-06 GCTAAAAATAATTACA 16 V_SOX14_03_M02798 TRANSFAC - 77961769 77961784 6.0E-06 TGTAATTATTTTTAGC 16 V_SOX14_03_M02798 TRANSFAC + 77961775 77961790 2.0E-06 AATAATTACAATACAA 16 V_SOX14_03_M02798 TRANSFAC - 77961775 77961790 1.0E-06 TTGTATTGTAATTATT 16 V_HOX13_02_M01452 TRANSFAC - 77961771 77961786 9.0E-06 ATTGTAATTATTTTTA 16 V_HOX13_02_M01452 TRANSFAC + 77961773 77961788 9.0E-06 AAAATAATTACAATAC 16 V_NF1_Q6_M00193 TRANSFAC + 77961756 77961773 3.0E-06 ATTTGGCAAACATGCTAA 18 V_NF1_Q6_M00193 TRANSFAC - 77961811 77961828 7.0E-06 ACTTGGCATGAATACTTT 18 V_HOXC8_01_M01321 TRANSFAC + 77961771 77961786 2.0E-06 TAAAAATAATTACAAT 16 V_HOXC8_01_M01321 TRANSFAC - 77961773 77961788 0.0E+00 GTATTGTAATTATTTT 16

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.