Search TFs or Genes

Construction and Validation

Optimal Promoter Size

Download

Citation and Contact

CES1 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 1066 carboxylesterase 1 chr16 - 55866575 - 55872075 55867075 Transcription Factor Binding Sites   Download all TFBS in the CES1 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints FOXB1_forkhead_DBD_dimeric_18_1 SELEX - 55867698 55867715 8.0E-06 TTGGTAAATGTTCACAAA 18 SP8_C2H2_DBD_monomeric_12_1 SELEX + 55867161 55867172 1.0E-06 GCCACGCCCACC 12 SP3_C2H2_DBD_monomeric_11_1 SELEX + 55867161 55867171 1.0E-06 GCCACGCCCAC 11 Tp53_p53l_DBD_dimeric_18_1 SELEX - 55867236 55867253 1.0E-06 ACAAGTAGTTGGGCAAGT 18 NFIA_NFI_full_dimeric_15_1 SELEX + 55867721 55867735 6.0E-06 TTGGCACCTGGCCAT 15 NFIA_NFI_full_dimeric_15_1 SELEX - 55867721 55867735 7.0E-06 ATGGCCAGGTGCCAA 15 KLF16_C2H2_DBD_monomeric_11_1 SELEX + 55867161 55867171 3.0E-06 GCCACGCCCAC 11 NHLH1_MA0048.1 JASPAR + 55866760 55866771 1.0E-05 GCTCAGCTGCTC 12 SOX9_HMG_full_dimeric_16_1 SELEX - 55870441 55870456 6.0E-06 CACAATCTGCAGAGTC 16 FOXG1_forkhead_DBD_dimeric_17_1 SELEX - 55868045 55868061 9.0E-06 ATAAATAGCTGTGCACA 17 SRF_MADS_DBD_dimeric_12_1 SELEX - 55866782 55866793 4.0E-06 TCCATATTAGGA 12 KLF14_C2H2_DBD_monomeric_14_1 SELEX + 55867160 55867173 1.0E-06 GGCCACGCCCACCC 14 TEF_bZIP_DBD_dimeric_12_1 SELEX + 55867251 55867262 9.0E-06 TGTTACATAAGG 12 FOXL1_forkhead_full_dimeric_13_1 SELEX - 55868054 55868066 2.0E-06 TGTTAATAAATAG 13 TBX1_TBX_DBD_dimeric_23_1 SELEX + 55867567 55867589 9.0E-06 TGTCACACACCATCGGTGTCAGA 23 TBX1_TBX_DBD_dimeric_23_1 SELEX - 55867567 55867589 1.0E-06 TCTGACACCGATGGTGTGTGACA 23 HLF_bZIP_full_dimeric_12_1 SELEX - 55867251 55867262 5.0E-06 CCTTATGTAACA 12 NFIX_NFI_full_dimeric_15_2 SELEX + 55867721 55867735 4.0E-06 TTGGCACCTGGCCAT 15 NFIX_NFI_full_dimeric_15_2 SELEX - 55867721 55867735 5.0E-06 ATGGCCAGGTGCCAA 15 NFIL3_MA0025.1 JASPAR - 55867250 55867260 1.0E-06 TTATGTAACAA 11 EBF1_MA0154.1 JASPAR - 55871643 55871652 5.0E-06 ACCCCAGGGA 10 DBP_bZIP_full_dimeric_12_1 SELEX - 55867251 55867262 9.0E-06 CCTTATGTAACA 12 MAFF_bZIP_DBD_dimeric_15_1 SELEX - 55870436 55870450 5.0E-06 CTGCAGAGTCATCAT 15 SRF_MA0083.1 JASPAR + 55866781 55866792 7.0E-06 GTCCTAATATGG 12 Klf4_MA0039.2 JASPAR - 55867161 55867170 1.0E-05 TGGGCGTGGC 10 OTX2_homeodomain_DBD_dimeric_15_1 SELEX + 55867084 55867098 8.0E-06 CCTAATCCTCTAATT 15 BARHL2_homeodomain_full_dimeric_16_1 SELEX + 55870496 55870511 8.0E-06 TAATTTTTGCTTAATA 16 POU4F3_POU_DBD_monomeric_16_1 SELEX - 55868057 55868072 9.0E-06 CTTCATTGTTAATAAA 16 Barhl1_homeodomain_DBD_dimeric_16_1 SELEX + 55870496 55870511 9.0E-06 TAATTTTTGCTTAATA 16 Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1 SELEX + 55867162 55867177 3.0E-06 CCACGCCCACCCACAG 16 CUX1_CUT_DBD_dimeric_18_1 SELEX + 55867741 55867758 9.0E-06 ATGGATACAAAGACCAAT 18 Foxc1_forkhead_DBD_dimeric_11_1 SELEX - 55868055 55868065 9.0E-06 GTTAATAAATA 11 HNF1A_homeodomain_full_dimeric_15_1 SELEX + 55868052 55868066 4.0E-06 AGCTATTTATTAACA 15 HNF1A_homeodomain_full_dimeric_15_1 SELEX - 55868052 55868066 3.0E-06 TGTTAATAAATAGCT 15 Lhx8_homeodomain_DBD_dimeric_18_1 SELEX - 55867093 55867110 9.0E-06 CTGATCTCTCCCAATTAG 18 HSF4_HSF_DBD_trimeric_13_1 SELEX - 55869831 55869843 8.0E-06 CTCCAGAAGTTTC 13 Mafb_bZIP_DBD_dimeric_17_1 SELEX + 55870435 55870451 4.0E-06 CATGATGACTCTGCAGA 17 Mafb_bZIP_DBD_dimeric_17_1 SELEX - 55870435 55870451 3.0E-06 TCTGCAGAGTCATCATG 17 SP4_C2H2_full_monomeric_17_1 SELEX + 55867158 55867174 0.0E+00 CAGGCCACGCCCACCCA 17 TFEB_bHLH_full_dimeric_10_1 SELEX + 55869767 55869776 3.0E-06 ATCACATGAC 10 MAFK_bZIP_full_dimeric_15_1 SELEX + 55870436 55870450 3.0E-06 ATGATGACTCTGCAG 15 MAFK_bZIP_full_dimeric_15_1 SELEX - 55870436 55870450 4.0E-06 CTGCAGAGTCATCAT 15 SP1_C2H2_DBD_monomeric_11_1 SELEX + 55867161 55867171 4.0E-06 GCCACGCCCAC 11 MAFK_bZIP_DBD_dimeric_21_1 SELEX + 55870433 55870453 0.0E+00 TTCATGATGACTCTGCAGATT 21 MAFK_bZIP_DBD_dimeric_21_1 SELEX - 55870433 55870453 1.0E-06 AATCTGCAGAGTCATCATGAA 21 HNF1B_homeodomain_full_dimeric_13_1 SELEX + 55868053 55868065 8.0E-06 GCTATTTATTAAC 13 HNF1B_homeodomain_full_dimeric_13_1 SELEX - 55868053 55868065 4.0E-06 GTTAATAAATAGC 13 HESX1_homeodomain_DBD_dimeric_15_1 SELEX + 55868057 55868071 9.0E-06 TTTATTAACAATGAA 15 Klf12_C2H2_DBD_monomeric_15_1 SELEX + 55867160 55867174 2.0E-06 GGCCACGCCCACCCA 15 NFIB_NFI_full_dimeric_15_1 SELEX + 55867721 55867735 7.0E-06 TTGGCACCTGGCCAT 15 NFIB_NFI_full_dimeric_15_1 SELEX - 55867721 55867735 7.0E-06 ATGGCCAGGTGCCAA 15 MAFG_bZIP_full_dimeric_21_1 SELEX + 55870433 55870453 0.0E+00 TTCATGATGACTCTGCAGATT 21 MAFG_bZIP_full_dimeric_21_1 SELEX - 55870433 55870453 0.0E+00 AATCTGCAGAGTCATCATGAA 21 Pou5f1_MA0142.1 JASPAR - 55867529 55867543 9.0E-06 TATTGTGAAGCTAAT 15 SRF_MADS_full_dimeric_16_1 SELEX - 55866780 55866795 1.0E-05 CTTCCATATTAGGACT 16 TBX21_TBX_full_dimeric_19_1 SELEX - 55867569 55867587 2.0E-06 TGACACCGATGGTGTGTGA 19 TFEC_bHLH_DBD_dimeric_10_1 SELEX + 55869767 55869776 2.0E-06 ATCACATGAC 10 THRB_nuclearreceptor_DBD_dimeric_19_1 SELEX - 55869704 55869722 6.0E-06 GTGGCCTGGACAAGGGCAG 19 HNF1B_homeodomain_full_dimeric_15_1 SELEX + 55868052 55868066 4.0E-06 AGCTATTTATTAACA 15 HNF1B_homeodomain_full_dimeric_15_1 SELEX - 55868052 55868066 3.0E-06 TGTTAATAAATAGCT 15 NFE2L2_MA0150.1 JASPAR + 55868164 55868174 3.0E-06 ATGACCCAGCA 11 NFE2L2_MA0150.1 JASPAR + 55870439 55870449 3.0E-06 ATGACTCTGCA 11 HNF1A_MA0046.1 JASPAR - 55868053 55868066 2.0E-06 TGTTAATAAATAGC 14 V_DMRT4_01_M01149 TRANSFAC - 55867247 55867259 1.0E-05 TATGTAACAAGTA 13 V_HOXA9_01_M01351 TRANSFAC + 55869757 55869773 8.0E-06 GCAGCCATAAATCACAT 17 V_SRF_Q6_M00186 TRANSFAC + 55866781 55866794 2.0E-06 GTCCTAATATGGAA 14 V_SRF_Q6_M00186 TRANSFAC - 55866781 55866794 1.0E-06 TTCCATATTAGGAC 14 V_DBX1_01_M01483 TRANSFAC - 55868051 55868067 7.0E-06 TTGTTAATAAATAGCTG 17 V_DBX1_01_M01483 TRANSFAC + 55868054 55868070 1.0E-06 CTATTTATTAACAATGA 17 V_FOXP3_Q4_M00992 TRANSFAC - 55867523 55867539 6.0E-06 GTGAAGCTAATTCAGGC 17 V_CDX2_Q5_01_M01659 TRANSFAC - 55868054 55868064 5.0E-06 TTAATAAATAG 11 V_DMRT3_01_M01148 TRANSFAC + 55867739 55867753 6.0E-06 TAATGGATACAAAGA 15 V_NF1_Q6_01_M00806 TRANSFAC - 55867719 55867735 4.0E-06 ATGGCCAGGTGCCAAGC 17 V_SREBP2_Q6_M01177 TRANSFAC + 55869716 55869727 8.0E-06 AGGCCACACCAC 12 V_NF1A_Q6_M02103 TRANSFAC - 55867720 55867735 6.0E-06 ATGGCCAGGTGCCAAG 16 V_GM397_03_M02760 TRANSFAC - 55868040 55868056 3.0E-06 TAGCTGTGCACATCACT 17 V_GM397_03_M02760 TRANSFAC + 55868041 55868057 3.0E-06 GTGATGTGCACAGCTAT 17 V_GATA3_03_M00351 TRANSFAC + 55870489 55870498 5.0E-06 ATAGATCTAA 10 V_POU5F1_02_M02245 TRANSFAC - 55867529 55867543 9.0E-06 TATTGTGAAGCTAAT 15 V_MEF2_02_M00231 TRANSFAC - 55868049 55868070 8.0E-06 TCATTGTTAATAAATAGCTGTG 22 V_MEF2_02_M00231 TRANSFAC - 55870490 55870511 4.0E-06 TATTAAGCAAAAATTAGATCTA 22 V_IRF_Q6_01_M00972 TRANSFAC + 55868201 55868211 6.0E-06 AGAACTGAAAG 11 V_RP58_01_M00532 TRANSFAC + 55871679 55871690 9.0E-06 AGAGCATCTGGA 12 V_CEBP_Q2_M00190 TRANSFAC - 55869678 55869691 9.0E-06 ACATTGGGAAAATA 14 V_GABPA_04_M02858 TRANSFAC + 55870422 55870437 4.0E-06 CCTTTTTCTGCTTCAT 16 V_GKLF_02_M01588 TRANSFAC + 55867161 55867172 3.0E-06 GCCACGCCCACC 12 V_AFP1_Q6_M00616 TRANSFAC - 55870493 55870503 9.0E-06 AAAAATTAGAT 11 V_HEN1_01_M00068 TRANSFAC + 55866755 55866776 3.0E-06 GCCGGGCTCAGCTGCTCCAAGT 22 V_BRN2_01_M00145 TRANSFAC - 55868056 55868071 0.0E+00 TTCATTGTTAATAAAT 16 V_NKX62_Q2_M00489 TRANSFAC - 55868053 55868064 7.0E-06 TTAATAAATAGC 12 V_TAL1_GATA1_01_M02243 TRANSFAC - 55870063 55870080 6.0E-06 CTTGTGGATAGAGATAGG 18 V_SRF_C_M00215 TRANSFAC - 55866779 55866793 2.0E-06 TCCATATTAGGACTT 15 V_PR_Q2_M00960 TRANSFAC - 55869672 55869681 9.0E-06 AATAGAACAT 10 V_DBP_Q6_01_M01872 TRANSFAC - 55867253 55867260 5.0E-06 TTATGTAA 8 V_E4BP4_01_M00045 TRANSFAC - 55867251 55867262 2.0E-06 CCTTATGTAACA 12 V_MYCMAX_02_M00123 TRANSFAC + 55869766 55869777 1.0E-05 AATCACATGACA 12 V_HNF1_Q6_M00790 TRANSFAC - 55868050 55868067 0.0E+00 TTGTTAATAAATAGCTGT 18 V_IRF2_01_M00063 TRANSFAC + 55868200 55868212 5.0E-06 GAGAACTGAAAGC 13 V_CEBPD_Q6_M00621 TRANSFAC + 55867079 55867090 6.0E-06 AATTGCCTAATC 12 V_CEBPB_02_M00117 TRANSFAC - 55870355 55870368 2.0E-06 TGTTTGCACAATTG 14 V_IRF_Q6_M00772 TRANSFAC - 55868201 55868215 4.0E-06 CATGCTTTCAGTTCT 15 V_HNF1_Q6_01_M01011 TRANSFAC + 55868049 55868069 0.0E+00 CACAGCTATTTATTAACAATG 21 V_SOX18_03_M02801 TRANSFAC - 55868057 55868072 1.0E-06 CTTCATTGTTAATAAA 16 Tal1_Gata1_MA0140.1 JASPAR - 55870063 55870080 6.0E-06 CTTGTGGATAGAGATAGG 18 V_PPARG_03_M00528 TRANSFAC - 55867702 55867718 8.0E-06 ATTTTGGTAAATGTTCA 17 V_BBX_04_M02843 TRANSFAC - 55868054 55868070 2.0E-06 TCATTGTTAATAAATAG 17 V_BBX_04_M02843 TRANSFAC + 55868055 55868071 7.0E-06 TATTTATTAACAATGAA 17 V_XFD2_01_M00268 TRANSFAC - 55868051 55868064 1.0E-05 TTAATAAATAGCTG 14 V_EBF1_01_M02267 TRANSFAC - 55871643 55871652 5.0E-06 ACCCCAGGGA 10 V_NCX_02_M01420 TRANSFAC + 55868051 55868067 9.0E-06 CAGCTATTTATTAACAA 17 V_NCX_02_M01420 TRANSFAC - 55868051 55868067 5.0E-06 TTGTTAATAAATAGCTG 17 V_NCX_02_M01420 TRANSFAC + 55868054 55868070 7.0E-06 CTATTTATTAACAATGA 17 V_SRF_Q5_02_M01007 TRANSFAC + 55866778 55866796 3.0E-06 CAAGTCCTAATATGGAAGT 19 V_SRF_Q5_02_M01007 TRANSFAC - 55866779 55866797 8.0E-06 GACTTCCATATTAGGACTT 19 V_ISGF3G_03_M02771 TRANSFAC + 55869824 55869838 8.0E-06 CTGAAATGAAACTTC 15 V_STAF_02_M00264 TRANSFAC + 55867707 55867727 1.0E-06 ATTTACCAAAATGCTTGGCAC 21 V_SOX11_03_M02795 TRANSFAC + 55868058 55868074 4.0E-06 TTATTAACAATGAAGAC 17 V_TBX5_01_M01019 TRANSFAC - 55870415 55870426 1.0E-06 AAAGGTGTCAGA 12 V_ICSBP_Q6_M00699 TRANSFAC + 55868202 55868213 7.0E-06 GAACTGAAAGCA 12 V_MAF_Q6_01_M00983 TRANSFAC - 55870439 55870449 2.0E-06 TGCAGAGTCAT 11 V_GATA4_Q3_M00632 TRANSFAC + 55867217 55867228 4.0E-06 AGATTACAGAGA 12 V_VBP_01_M00228 TRANSFAC + 55867252 55867261 3.0E-06 GTTACATAAG 10 V_GFI1_Q6_M01067 TRANSFAC - 55867608 55867620 5.0E-06 AAAAATCCCTGCT 13 V_GFI1_Q6_M01067 TRANSFAC + 55869763 55869775 8.0E-06 ATAAATCACATGA 13 V_SOX15_03_M02799 TRANSFAC + 55868058 55868074 9.0E-06 TTATTAACAATGAAGAC 17 V_GATA1_05_M00346 TRANSFAC - 55867665 55867674 6.0E-06 GATGATAACA 10 V_ISX_01_M01331 TRANSFAC + 55867089 55867104 8.0E-06 TCCTCTAATTGGGAGA 16 V_ISX_01_M01331 TRANSFAC - 55867089 55867104 3.0E-06 TCTCCCAATTAGAGGA 16 V_HNF1_01_M00132 TRANSFAC - 55867699 55867713 4.0E-06 GGTAAATGTTCACAA 15 V_HNF1_01_M00132 TRANSFAC - 55868052 55868066 5.0E-06 TGTTAATAAATAGCT 15 V_TFEB_01_M01768 TRANSFAC + 55869767 55869776 7.0E-06 ATCACATGAC 10 V_TFEB_01_M01768 TRANSFAC - 55869767 55869776 7.0E-06 GTCATGTGAT 10 V_LUN1_01_M00480 TRANSFAC + 55869652 55869668 1.0E-06 TACCAGGTACCTGGGGA 17 V_GATA3_01_M00077 TRANSFAC - 55870062 55870070 4.0E-06 GAGATAGGG 9 V_NKX22_01_M00485 TRANSFAC - 55867244 55867253 7.0E-06 ACAAGTAGTT 10 V_NRF2_Q4_M00821 TRANSFAC - 55870438 55870450 1.0E-06 CTGCAGAGTCATC 13 V_SRF_01_M00152 TRANSFAC + 55866779 55866796 0.0E+00 AAGTCCTAATATGGAAGT 18 V_P53_04_M01652 TRANSFAC + 55869696 55869715 8.0E-06 TGGCAAGCCTGCCCTTGTCC 20 V_PLZF_02_M01075 TRANSFAC - 55870470 55870498 9.0E-06 TTAGATCTATTGTAAGGCTTGGTAGGCTC 29 V_LHX61_02_M01422 TRANSFAC - 55867088 55867104 5.0E-06 TCTCCCAATTAGAGGAT 17 V_SRF_Q5_01_M00922 TRANSFAC - 55866778 55866792 6.0E-06 CCATATTAGGACTTG 15 V_SRF_Q4_M00810 TRANSFAC - 55866776 55866793 4.0E-06 TCCATATTAGGACTTGGA 18 V_OCT1_06_M00162 TRANSFAC - 55867625 55867638 7.0E-06 CATTTTTACATTCT 14 V_HSF_Q6_M00641 TRANSFAC - 55869831 55869843 2.0E-06 CTCCAGAAGTTTC 13 V_IRF1_Q6_01_M01881 TRANSFAC - 55868200 55868213 8.0E-06 TGCTTTCAGTTCTC 14 V_SRF_02_M01257 TRANSFAC - 55866777 55866794 7.0E-06 TTCCATATTAGGACTTGG 18 V_SRF_02_M01257 TRANSFAC + 55866781 55866798 4.0E-06 GTCCTAATATGGAAGTCG 18 V_SOX8_03_M02808 TRANSFAC - 55868058 55868074 2.0E-06 GTCTTCATTGTTAATAA 17 V_SOX14_04_M02901 TRANSFAC - 55867684 55867700 1.0E-06 AAAATGGATGGGTACTT 17 V_GATA2_03_M00349 TRANSFAC + 55867102 55867111 9.0E-06 AGAGATCAGA 10 V_VMAF_01_M00035 TRANSFAC + 55870434 55870452 0.0E+00 TCATGATGACTCTGCAGAT 19 V_NFE2_Q6_M02104 TRANSFAC + 55868163 55868178 7.0E-06 TATGACCCAGCAATTC 16 V_HNF1A_Q5_M02013 TRANSFAC - 55868056 55868066 6.0E-06 TGTTAATAAAT 11 V_HOXD8_01_M01432 TRANSFAC - 55868051 55868067 2.0E-06 TTGTTAATAAATAGCTG 17 V_SOX12_03_M02796 TRANSFAC - 55868057 55868070 1.0E-06 TCATTGTTAATAAA 14 V_SOX15_04_M02903 TRANSFAC - 55867495 55867509 3.0E-06 CTCGATGAAATTTAA 15 V_GLI_Q2_M01037 TRANSFAC + 55870087 55870098 5.0E-06 ATTGGGAGGTCC 12 V_CTF1_01_M01196 TRANSFAC - 55867721 55867734 3.0E-06 TGGCCAGGTGCCAA 14 V_CTF1_01_M01196 TRANSFAC + 55867722 55867735 2.0E-06 TGGCACCTGGCCAT 14 V_NFE2L2_01_M02263 TRANSFAC + 55868164 55868174 3.0E-06 ATGACCCAGCA 11 V_NFE2L2_01_M02263 TRANSFAC + 55870439 55870449 3.0E-06 ATGACTCTGCA 11 V_TFE_Q6_M01029 TRANSFAC - 55869768 55869775 1.0E-05 TCATGTGA 8 V_MAFK_04_M02880 TRANSFAC + 55868137 55868151 8.0E-06 TCAAAAAGTTCAACA 15 V_GATA1_02_M00126 TRANSFAC - 55870060 55870073 1.0E-05 ATAGAGATAGGGAT 14 V_ZFP128_04_M02932 TRANSFAC + 55870506 55870519 1.0E-06 TTAATACATATAAC 14 V_ZFP128_04_M02932 TRANSFAC - 55870506 55870519 9.0E-06 GTTATATGTATTAA 14 V_BARX1_01_M01340 TRANSFAC + 55867074 55867089 7.0E-06 CTGCCAATTGCCTAAT 16 V_TAACC_B_M00331 TRANSFAC - 55867449 55867471 5.0E-06 TGGAAAGCTATGAAAACACAAGC 23 V_HNF1A_01_M02162 TRANSFAC - 55868053 55868066 2.0E-06 TGTTAATAAATAGC 14 TLX1_NFIC_MA0119.1 JASPAR - 55867721 55867734 3.0E-06 TGGCCAGGTGCCAA 14 TLX1_NFIC_MA0119.1 JASPAR + 55867722 55867735 2.0E-06 TGGCACCTGGCCAT 14 V_GLIS2_04_M02863 TRANSFAC - 55868055 55868068 1.0E-06 ATTGTTAATAAATA 14 V_GLIS2_04_M02863 TRANSFAC + 55868057 55868070 4.0E-06 TTTATTAACAATGA 14 V_CEBPG_Q6_01_M01869 TRANSFAC - 55867079 55867090 6.0E-06 GATTAGGCAATT 12 V_NANOG_02_M01247 TRANSFAC + 55868056 55868075 3.0E-06 ATTTATTAACAATGAAGACA 20 V_OCT4_01_M01125 TRANSFAC - 55867529 55867543 6.0E-06 TATTGTGAAGCTAAT 15 V_HSF1_Q6_01_M02017 TRANSFAC + 55869831 55869844 2.0E-06 GAAACTTCTGGAGA 14 V_OTX3_01_M01403 TRANSFAC - 55867081 55867097 4.0E-06 ATTAGAGGATTAGGCAA 17

Need help? Please contact cplaisier(at)systemsbiology.org if you have any questions, comments or concerns. Developed at the Institute for Systems Biology in the Baliga Lab.