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DSCR4 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 10281 Down syndrome critical region gene 4 chr21 - 39492954 - 39498454 39493454 Transcription Factor Binding Sites   Download all TFBS in the DSCR4 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints FOXG1_forkhead_DBD_dimeric_17_1 SELEX - 39493700 39493716 0.0E+00 AACAACAACAAAAAACA 17 FOXG1_forkhead_DBD_dimeric_17_1 SELEX + 39494690 39494706 2.0E-06 CTAAACAACTAAAAACT 17 POU5F1P1_POU_DBD_monomeric_9_1 SELEX + 39493585 39493593 2.0E-06 TATGCAAAT 9 FOXO3_MA0157.1 JASPAR + 39493635 39493642 7.0E-06 TGTAAACA 8 FOXD1_MA0031.1 JASPAR + 39493636 39493643 7.0E-06 GTAAACAT 8 POU2F3_POU_DBD_monomeric_9_1 SELEX + 39493585 39493593 2.0E-06 TATGCAAAT 9 PAX5_PAX_DBD_monomeric_18_1 SELEX + 39493350 39493367 7.0E-06 GGACACACATGGGTGAGT 18 POU1F1_POU_DBD_monomeric_14_1 SELEX + 39493583 39493596 4.0E-06 GTTATGCAAATAGG 14 BARX1_homeodomain_DBD_monomeric_8_1 SELEX - 39494597 39494604 5.0E-06 ACAATTAA 8 SOX15_HMG_full_dimeric_15_3 SELEX + 39494578 39494592 6.0E-06 ATGAGTAACTTACAT 15 POU2F2_POU_DBD_monomeric_11_1 SELEX + 39493584 39493594 1.0E-06 TTATGCAAATA 11 POU3F4_POU_DBD_monomeric_9_1 SELEX + 39493585 39493593 2.0E-06 TATGCAAAT 9 Pou2f2_POU_DBD_monomeric_9_1 SELEX + 39493585 39493593 2.0E-06 TATGCAAAT 9 POU3F3_POU_DBD_monomeric_13_1 SELEX + 39493583 39493595 5.0E-06 GTTATGCAAATAG 13 FOXJ3_forkhead_DBD_dimeric_14_1 SELEX - 39493700 39493713 3.0E-06 AACAACAAAAAACA 14 POU3F1_POU_DBD_monomeric_12_1 SELEX + 39493584 39493595 2.0E-06 TTATGCAAATAG 12 IRF9_IRF_full_trimeric_15_1 SELEX - 39493746 39493760 6.0E-06 AACAAGAGCGAAACT 15 Pou5f1_MA0142.1 JASPAR + 39493579 39493593 0.0E+00 TCTTGTTATGCAAAT 15 POU2F1_POU_DBD_monomeric_12_1 SELEX + 39493583 39493594 1.0E-06 GTTATGCAAATA 12 FOXB1_forkhead_full_monomeric_9_1 SELEX + 39493635 39493643 3.0E-06 TGTAAACAT 9 POU3F2_POU_DBD_monomeric_12_1 SELEX + 39493584 39493595 3.0E-06 TTATGCAAATAG 12 Foxj3_forkhead_DBD_dimeric_13_1 SELEX - 39493707 39493719 5.0E-06 AACAACAACAACA 13 Sox1_HMG_DBD_dimeric_15_2 SELEX + 39494582 39494596 8.0E-06 GTAACTTACATTCTC 15 FOXJ2_forkhead_DBD_dimeric_14_1 SELEX - 39493700 39493713 1.0E-06 AACAACAAAAAACA 14 V_MEQ_01_M02049 TRANSFAC + 39493351 39493359 9.0E-06 GACACACAT 9 V_FOXP1_01_M00987 TRANSFAC + 39493700 39493719 2.0E-06 TGTTTTTTGTTGTTGTTGTT 20 V_GAF_Q6_M01209 TRANSFAC - 39494662 39494672 5.0E-06 CAAATTCCTGT 11 V_FOXO3_02_M02270 TRANSFAC + 39493635 39493642 7.0E-06 TGTAAACA 8 V_SRY_07_M02813 TRANSFAC + 39494596 39494611 4.0E-06 CTTAATTGTAATGGTT 16 V_POU5F1_02_M02245 TRANSFAC + 39493579 39493593 0.0E+00 TCTTGTTATGCAAAT 15 V_OCT1_Q5_01_M00930 TRANSFAC - 39493585 39493595 8.0E-06 CTATTTGCATA 11 V_NFAT3_Q3_M01734 TRANSFAC - 39494628 39494637 1.0E-05 TCATTTTCCA 10 V_OCT1_01_M00135 TRANSFAC + 39493580 39493598 1.0E-06 CTTGTTATGCAAATAGGCT 19 V_GTF2IRD1_01_M01229 TRANSFAC - 39493685 39493693 7.0E-06 GGGATTAGG 9 V_POU2F3_01_M01476 TRANSFAC + 39493582 39493597 2.0E-06 TGTTATGCAAATAGGC 16 V_FOXO3A_Q1_M01137 TRANSFAC + 39494689 39494700 5.0E-06 TCTAAACAACTA 12 V_SOX11_04_M02899 TRANSFAC + 39494597 39494610 9.0E-06 TTAATTGTAATGGT 14 V_CACCCBINDINGFACTOR_Q6_M00721 TRANSFAC - 39493568 39493583 1.0E-06 CAAGATTAGGGTGGGG 16 V_SOX21_03_M02803 TRANSFAC + 39494596 39494611 6.0E-06 CTTAATTGTAATGGTT 16 V_SOX21_03_M02803 TRANSFAC - 39494596 39494611 3.0E-06 AACCATTACAATTAAG 16 V_NFAT2_01_M01748 TRANSFAC + 39494627 39494635 8.0E-06 GTGGAAAAT 9 V_ZFP105_03_M02827 TRANSFAC - 39493703 39493717 9.0E-06 CAACAACAACAAAAA 15 V_NKX61_01_M00424 TRANSFAC + 39494594 39494606 7.0E-06 CTCTTAATTGTAA 13 V_IRF2_01_M00063 TRANSFAC - 39493746 39493758 1.0E-05 CAAGAGCGAAACT 13 V_FOXK1_04_M02856 TRANSFAC - 39493701 39493715 6.0E-06 ACAACAACAAAAAAC 15 V_FOXK1_04_M02856 TRANSFAC - 39493704 39493718 0.0E+00 ACAACAACAACAAAA 15 V_FOXK1_04_M02856 TRANSFAC - 39493707 39493721 1.0E-06 GCAACAACAACAACA 15 V_NKX25_02_M00241 TRANSFAC + 39494596 39494603 7.0E-06 CTTAATTG 8 V_HOXC11_01_M01329 TRANSFAC - 39493336 39493351 8.0E-06 CCATGTCGTTAATCAT 16 V_OCAB_Q6_M02113 TRANSFAC + 39493584 39493594 2.0E-06 TTATGCAAATA 11 V_XFD2_01_M00268 TRANSFAC + 39493633 39493646 7.0E-06 TCTGTAAACATGGG 14 V_STAT4_Q5_M02117 TRANSFAC + 39493429 39493438 1.0E-05 TTAAGGGAAA 10 V_OCT4_02_M01124 TRANSFAC + 39493580 39493594 7.0E-06 CTTGTTATGCAAATA 15 V_SOX11_03_M02795 TRANSFAC - 39493699 39493715 8.0E-06 ACAACAACAAAAAACAC 17 V_OCT1_B_M00342 TRANSFAC + 39493585 39493594 0.0E+00 TATGCAAATA 10 V_OCT_Q6_M00795 TRANSFAC - 39493585 39493595 3.0E-06 CTATTTGCATA 11 V_PAX8_B_M00328 TRANSFAC + 39493352 39493369 1.0E-06 ACACACATGGGTGAGTTA 18 V_EVI1_06_M00011 TRANSFAC - 39493576 39493584 7.0E-06 ACAAGATTA 9 V_POU5F1_01_M01307 TRANSFAC + 39493585 39493594 2.0E-06 TATGCAAATA 10 V_FAC1_01_M00456 TRANSFAC - 39493700 39493713 6.0E-06 AACAACAAAAAACA 14 V_FAC1_01_M00456 TRANSFAC - 39493703 39493716 0.0E+00 AACAACAACAAAAA 14 V_FAC1_01_M00456 TRANSFAC - 39493706 39493719 9.0E-06 AACAACAACAACAA 14 V_OCT2_01_M01368 TRANSFAC + 39493582 39493597 1.0E-06 TGTTATGCAAATAGGC 16 V_CAAT_C_M00200 TRANSFAC - 39493498 39493522 0.0E+00 ACCAATCTCTGGGCTCCACGTAAAT 25 V_FOXL1_02_M02857 TRANSFAC + 39494686 39494701 2.0E-06 AATTCTAAACAACTAA 16 V_FOXL1_04_M02753 TRANSFAC + 39493631 39493647 7.0E-06 TTTCTGTAAACATGGGT 17 V_FOXO3_01_M00477 TRANSFAC - 39494687 39494700 2.0E-06 TAGTTGTTTAGAAT 14 V_ASCL2_04_M02841 TRANSFAC + 39493564 39493579 1.0E-06 GTCACCCCACCCTAAT 16 V_NFAT2_02_M01749 TRANSFAC - 39494609 39494619 6.0E-06 TTCCAAGGAAC 11 V_NFAT2_02_M01749 TRANSFAC + 39494610 39494620 2.0E-06 TTCCTTGGAAA 11 V_SREBP1_02_M00221 TRANSFAC + 39493563 39493573 2.0E-06 GGTCACCCCAC 11 V_SOX14_03_M02798 TRANSFAC + 39494596 39494611 8.0E-06 CTTAATTGTAATGGTT 16 V_CEBPA_Q6_M01866 TRANSFAC + 39493581 39493593 2.0E-06 TTGTTATGCAAAT 13 V_OCT4_01_M01125 TRANSFAC + 39493579 39493593 1.0E-06 TCTTGTTATGCAAAT 15

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