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HCN4 Entrez Description Chrom. Strand Promoter (Start - Stop) TSS 10021 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 chr15 - 73661105 - 73666605 73661605 Transcription Factor Binding Sites   Download all TFBS in the HCN4 promoter   Motif Source Strand Start Stop PValue Match Sequence Overlap w/ Footprints HSF2_HSF_DBD_trimeric_13_1 SELEX - 73664530 73664542 6.0E-06 TTCCAGAATTTCC 13 HSF2_HSF_DBD_trimeric_13_1 SELEX + 73664535 73664547 8.0E-06 TTCTGGAAGCTTA 13 Sox1_HMG_DBD_dimeric_14_1 SELEX + 73658576 73658589 7.0E-06 TGACTGGTCATTCC 14 Sox1_HMG_DBD_dimeric_14_1 SELEX - 73658576 73658589 6.0E-06 GGAATGACCAGTCA 14 SOX10_HMG_full_dimeric_15_3 SELEX + 73659015 73659029 2.0E-06 CTGACTGGCAGTCAT 15 SOX10_HMG_full_dimeric_15_3 SELEX - 73659015 73659029 5.0E-06 ATGACTGCCAGTCAG 15 IRF7_IRF_DBD_dimeric_14_1 SELEX - 73662705 73662718 6.0E-06 TCAAAAGTAAAAAT 14 KLF16_C2H2_DBD_monomeric_11_1 SELEX + 73660922 73660932 1.0E-05 GCCCCGCCCCC 11 SOX21_HMG_DBD_dimeric_13_2 SELEX + 73659016 73659028 1.0E-05 TGACTGGCAGTCA 13 SOX9_HMG_full_dimeric_17_3 SELEX + 73659014 73659030 3.0E-06 CCTGACTGGCAGTCATA 17 SOX9_HMG_full_dimeric_17_3 SELEX - 73659014 73659030 3.0E-06 TATGACTGCCAGTCAGG 17 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX + 73660734 73660744 3.0E-06 AGCCTCAGGCG 11 TFAP2B_TFAP_DBD_dimeric_11_1 SELEX - 73660734 73660744 7.0E-06 CGCCTGAGGCT 11 EWSR1-FLI1_MA0149.1 JASPAR + 73658519 73658536 5.0E-06 GGAAAAAAGGGGGGAGGG 18 EWSR1-FLI1_MA0149.1 JASPAR - 73660859 73660876 5.0E-06 GGAGGGAGGCAAGAAGGG 18 EWSR1-FLI1_MA0149.1 JASPAR - 73660860 73660877 1.0E-06 GGGAGGGAGGCAAGAAGG 18 EWSR1-FLI1_MA0149.1 JASPAR - 73660863 73660880 4.0E-06 GGAGGGAGGGAGGCAAGA 18 EWSR1-FLI1_MA0149.1 JASPAR - 73660864 73660881 1.0E-06 GGGAGGGAGGGAGGCAAG 18 GLI2_C2H2_DBD_monomeric_14_1 SELEX + 73662652 73662665 7.0E-06 GACCTCCCACAGTG 14 SOX7_HMG_full_dimeric_17_2 SELEX - 73659014 73659030 6.0E-06 TATGACTGCCAGTCAGG 17 Tcfap2a_TFAP_DBD_dimeric_13_1 SELEX + 73660390 73660402 9.0E-06 TGCCCCGAGGGCC 13 Tcfap2a_TFAP_DBD_dimeric_13_1 SELEX - 73660390 73660402 9.0E-06 GGCCCTCGGGGCA 13 SOX8_HMG_DBD_dimeric_14_1 SELEX - 73658576 73658589 8.0E-06 GGAATGACCAGTCA 14 SOX15_HMG_full_dimeric_15_3 SELEX + 73659015 73659029 5.0E-06 CTGACTGGCAGTCAT 15 SOX15_HMG_full_dimeric_15_3 SELEX - 73659015 73659029 9.0E-06 ATGACTGCCAGTCAG 15 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX + 73660734 73660744 3.0E-06 AGCCTCAGGCG 11 TFAP2A_TFAP_DBD_dimeric_11_1 SELEX - 73660734 73660744 8.0E-06 CGCCTGAGGCT 11 Creb5_bZIP_DBD_dimeric_12_1 SELEX + 73662683 73662694 5.0E-06 GATGACATCACT 12 TFAP2C_TFAP_full_dimeric_13_1 SELEX + 73660390 73660402 2.0E-06 TGCCCCGAGGGCC 13 TFAP2C_TFAP_full_dimeric_13_1 SELEX - 73660390 73660402 9.0E-06 GGCCCTCGGGGCA 13 JDP2_bZIP_full_dimeric_12_1 SELEX + 73662683 73662694 7.0E-06 GATGACATCACT 12 SOX8_HMG_full_dimeric_13_1 SELEX - 73659017 73659029 7.0E-06 ATGACTGCCAGTC 13 Sox17_HMG_DBD_dimeric_15_2 SELEX + 73659015 73659029 5.0E-06 CTGACTGGCAGTCAT 15 Sox17_HMG_DBD_dimeric_15_2 SELEX - 73659015 73659029 4.0E-06 ATGACTGCCAGTCAG 15 SOX2_HMG_full_dimeric_15_1 SELEX + 73659015 73659029 1.0E-06 CTGACTGGCAGTCAT 15 SOX2_HMG_full_dimeric_15_1 SELEX - 73659015 73659029 1.0E-06 ATGACTGCCAGTCAG 15 Pou2f2_POU_DBD_dimeric_14_1 SELEX + 73661244 73661257 8.0E-06 CCGGAATATTCATG 14 Pou2f2_POU_DBD_dimeric_14_1 SELEX - 73661244 73661257 9.0E-06 CATGAATATTCCGG 14 SP1_MA0079.2 JASPAR - 73658528 73658537 3.0E-06 CCCCTCCCCC 10 SP1_MA0079.2 JASPAR + 73660923 73660932 7.0E-06 CCCCGCCCCC 10 CREB3_bZIP_full_dimeric_14_1 SELEX - 73662682 73662695 3.0E-06 CAGTGATGTCATCA 14 BCL6B_C2H2_DBD_monomeric_17_1 SELEX - 73661954 73661970 6.0E-06 CCCTTTCTCGGAACTAC 17 SOX14_HMG_DBD_dimeric_15_1 SELEX + 73659015 73659029 1.0E-06 CTGACTGGCAGTCAT 15 SOX14_HMG_DBD_dimeric_15_1 SELEX - 73659015 73659029 1.0E-06 ATGACTGCCAGTCAG 15 TFAP2A_TFAP_DBD_dimeric_13_1 SELEX + 73660390 73660402 9.0E-06 TGCCCCGAGGGCC 13 RFX5_RFX_DBD_dimeric_16_3 SELEX + 73661276 73661291 8.0E-06 GGTTGCCATAGGAGCG 16 RFX5_RFX_DBD_dimeric_16_3 SELEX - 73661276 73661291 8.0E-06 CGCTCCTATGGCAACC 16 INSM1_MA0155.1 JASPAR + 73658991 73659002 9.0E-06 TGGAAGGGGGCA 12 Stat3_MA0144.1 JASPAR + 73666190 73666199 5.0E-06 TTCCGGGAAA 10 TFAP2C_TFAP_full_dimeric_11_1 SELEX + 73660734 73660744 4.0E-06 AGCCTCAGGCG 11 TFAP2C_TFAP_full_dimeric_11_1 SELEX - 73660734 73660744 9.0E-06 CGCCTGAGGCT 11 TFAP2B_TFAP_DBD_dimeric_13_1 SELEX + 73660390 73660402 8.0E-06 TGCCCCGAGGGCC 13 SOX18_HMG_full_dimeric_15_3 SELEX + 73659015 73659029 7.0E-06 CTGACTGGCAGTCAT 15 SOX18_HMG_full_dimeric_15_3 SELEX - 73659015 73659029 4.0E-06 ATGACTGCCAGTCAG 15 Sox3_HMG_DBD_dimeric_17_3 SELEX + 73659014 73659030 4.0E-06 CCTGACTGGCAGTCATA 17 Sox3_HMG_DBD_dimeric_17_3 SELEX - 73659014 73659030 1.0E-06 TATGACTGCCAGTCAGG 17 TP53_MA0106.1 JASPAR + 73658046 73658065 1.0E-06 CTGGGCATGCCTGGGGTTGG 20 BATF3_bZIP_DBD_dimeric_14_1 SELEX + 73662682 73662695 5.0E-06 TGATGACATCACTG 14 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX + 73660734 73660744 4.0E-06 AGCCTCAGGCG 11 Tcfap2a_TFAP_DBD_dimeric_11_1 SELEX - 73660734 73660744 4.0E-06 CGCCTGAGGCT 11 Sox1_HMG_DBD_dimeric_15_2 SELEX + 73659015 73659029 1.0E-06 CTGACTGGCAGTCAT 15 Sox1_HMG_DBD_dimeric_15_2 SELEX - 73659015 73659029 1.0E-06 ATGACTGCCAGTCAG 15 RREB1_MA0073.1 JASPAR + 73666197 73666216 6.0E-06 AAACAAACCAACCAGCCAGA 20 V_STAT5A_Q6_M01890 TRANSFAC - 73661958 73661970 7.0E-06 CCCTTTCTCGGAA 13 V_FXR_Q3_M00631 TRANSFAC + 73659448 73659461 1.0E-05 CAGGCTGAATGACC 14 V_NF1_Q6_01_M00806 TRANSFAC + 73666260 73666276 4.0E-06 ATGGATGGAGGCCAAGA 17 V_SP1_Q6_01_M00931 TRANSFAC - 73660922 73660931 4.0E-06 GGGGCGGGGC 10 V_MEF2_02_M00231 TRANSFAC - 73658546 73658567 1.0E-06 TCGGTGGCTTAAAATAGGTAGT 22 V_RFX4_03_M02789 TRANSFAC - 73659406 73659420 6.0E-06 CCTCTTAGCAACGGG 15 V_MAF_Q6_M00648 TRANSFAC + 73662788 73662803 9.0E-06 TGAGAAGAAGTGTTCT 16 V_GABPA_04_M02858 TRANSFAC - 73658513 73658528 9.0E-06 CCTTTTTTCCTTTGAC 16 V_STAT5B_01_M00459 TRANSFAC - 73661878 73661892 1.0E-05 CATTTCCTCGAAGTC 15 V_STAT5B_01_M00459 TRANSFAC - 73666187 73666201 5.0E-06 TGTTTCCCGGAACAT 15 V_SP1_03_M02281 TRANSFAC - 73658528 73658537 3.0E-06 CCCCTCCCCC 10 V_SP1_03_M02281 TRANSFAC + 73660923 73660932 7.0E-06 CCCCGCCCCC 10 V_JUNDM2_03_M02772 TRANSFAC - 73662681 73662696 6.0E-06 CCAGTGATGTCATCAC 16 V_OCT2_02_M01761 TRANSFAC + 73661246 73661255 3.0E-06 GGAATATTCA 10 V_OCT2_02_M01761 TRANSFAC - 73661246 73661255 1.0E-06 TGAATATTCC 10 V_MEF2A_Q6_M02024 TRANSFAC + 73658552 73658561 2.0E-06 TATTTTAAGC 10 V_STAT4_Q4_M01666 TRANSFAC + 73666190 73666203 6.0E-06 TTCCGGGAAACAAA 14 V_HELIOSA_02_M01004 TRANSFAC + 73658515 73658525 1.0E-05 CAAAGGAAAAA 11 V_OCT1_02_M00136 TRANSFAC + 73661245 73661259 1.0E-06 CGGAATATTCATGAA 15 V_SOX8_04_M02912 TRANSFAC + 73661249 73661262 8.0E-06 ATATTCATGAAGCC 14 V_NFAT_Q6_M00302 TRANSFAC + 73658515 73658526 2.0E-06 CAAAGGAAAAAA 12 V_STAT1_01_M00224 TRANSFAC + 73666184 73666204 8.0E-06 TAGATGTTCCGGGAAACAAAC 21 V_SP1_Q6_M00196 TRANSFAC + 73658527 73658539 5.0E-06 GGGGGGAGGGGCT 13 V_SP1_Q6_M00196 TRANSFAC - 73660921 73660933 2.0E-06 CGGGGGCGGGGCG 13 V_IRF3_Q3_M01279 TRANSFAC - 73658516 73658528 4.0E-06 CCTTTTTTCCTTT 13 V_IRF3_Q3_M01279 TRANSFAC + 73662703 73662715 5.0E-06 GCATTTTTACTTT 13 V_MAZ_Q6_01_M02023 TRANSFAC + 73658153 73658166 1.0E-06 AAGGGAGGGGAGGG 14 V_MAZ_Q6_01_M02023 TRANSFAC - 73660870 73660883 3.0E-06 GAGGGAGGGAGGGA 14 V_HNF3_Q6_M00791 TRANSFAC - 73664544 73664556 3.0E-06 ATAAGCAAATAAG 13 V_HNF3ALPHA_Q6_M00724 TRANSFAC + 73664546 73664556 2.0E-06 TATTTGCTTAT 11 V_EGR1_Q6_M01873 TRANSFAC - 73660925 73660934 4.0E-06 GCGGGGGCGG 10 V_STAT5A_02_M00460 TRANSFAC - 73666175 73666198 5.0E-06 TTCCCGGAACATCTATATCCAGTC 24 V_MEF2_03_M00232 TRANSFAC - 73658546 73658567 2.0E-06 TCGGTGGCTTAAAATAGGTAGT 22 V_RFXDC2_03_M02790 TRANSFAC - 73659406 73659420 2.0E-06 CCTCTTAGCAACGGG 15 V_MEF2_04_M00233 TRANSFAC - 73658546 73658567 0.0E+00 TCGGTGGCTTAAAATAGGTAGT 22 V_MEF2_Q6_01_M00941 TRANSFAC + 73658549 73658560 4.0E-06 ACCTATTTTAAG 12 V_SP1_01_M00008 TRANSFAC + 73658997 73659006 7.0E-06 GGGGCAGGGT 10 V_STAT3_03_M01595 TRANSFAC + 73666188 73666203 5.0E-06 TGTTCCGGGAAACAAA 16 V_INSM1_01_M02268 TRANSFAC + 73658991 73659002 9.0E-06 TGGAAGGGGGCA 12 V_MAF_Q6_01_M00983 TRANSFAC - 73659487 73659497 7.0E-06 TGCAGAGTCAG 11 V_TFIII_Q6_M00706 TRANSFAC - 73660876 73660884 6.0E-06 AGAGGGAGG 9 V_SP4_Q5_M01273 TRANSFAC - 73658528 73658538 5.0E-06 GCCCCTCCCCC 11 V_SP4_Q5_M01273 TRANSFAC + 73660922 73660932 1.0E-06 GCCCCGCCCCC 11 V_RARA_04_M02891 TRANSFAC - 73659453 73659468 1.0E-05 AGCTCCGGGTCATTCA 16 V_TTF1_Q5_M02034 TRANSFAC + 73666224 73666237 7.0E-06 AAGCCCTTGGGTGC 14 V_NANOG_01_M01123 TRANSFAC - 73666385 73666396 5.0E-06 AGGATCATTGCC 12 V_CPHX_01_M01478 TRANSFAC - 73662680 73662693 5.0E-06 GTGATGTCATCACC 14 V_CPHX_01_M01478 TRANSFAC + 73662681 73662694 2.0E-06 GTGATGACATCACT 14 V_FPM315_01_M01587 TRANSFAC + 73659506 73659517 0.0E+00 GGGGGAGGAGGA 12 V_NRF2_Q4_M00821 TRANSFAC - 73659486 73659498 1.0E-06 CTGCAGAGTCAGG 13 V_STAT_01_M00223 TRANSFAC - 73666190 73666198 7.0E-06 TTCCCGGAA 9 V_STAT1STAT1_Q3_M01212 TRANSFAC - 73666188 73666200 0.0E+00 GTTTCCCGGAACA 13 V_NRF1_Q6_M00652 TRANSFAC + 73660580 73660589 8.0E-06 CGCTTGCGCA 10 V_P53_04_M01652 TRANSFAC + 73658048 73658067 1.0E-05 GGGCATGCCTGGGGTTGGCC 20 V_ZFP281_01_M01597 TRANSFAC + 73658527 73658537 2.0E-06 GGGGGGAGGGG 11 V_SREBP_Q3_M00776 TRANSFAC - 73662677 73662688 4.0E-06 GTCATCACCCTA 12 V_STAT5A_01_M00457 TRANSFAC + 73661878 73661892 4.0E-06 GACTTCGAGGAAATG 15 V_HFH3_01_M00289 TRANSFAC + 73664543 73664555 3.0E-06 GCTTATTTGCTTA 13 V_HSF2_02_M01244 TRANSFAC + 73664530 73664542 9.0E-06 GGAAATTCTGGAA 13 V_EWSR1FLI1_01_M02252 TRANSFAC + 73658519 73658536 5.0E-06 GGAAAAAAGGGGGGAGGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC - 73660859 73660876 5.0E-06 GGAGGGAGGCAAGAAGGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC - 73660860 73660877 1.0E-06 GGGAGGGAGGCAAGAAGG 18 V_EWSR1FLI1_01_M02252 TRANSFAC - 73660863 73660880 4.0E-06 GGAGGGAGGGAGGCAAGA 18 V_EWSR1FLI1_01_M02252 TRANSFAC - 73660864 73660881 1.0E-06 GGGAGGGAGGGAGGCAAG 18 V_NFE2_Q6_M02104 TRANSFAC + 73659486 73659501 6.0E-06 CCTGACTCTGCAGCCT 16 V_PR_02_M00957 TRANSFAC - 73659571 73659597 7.0E-06 GACAGAATGAAAAGGTGTTCTGAGCCT 27 V_HNF3B_Q6_M02014 TRANSFAC + 73664545 73664553 1.0E-05 TTATTTGCT 9 V_IRF1_01_M00062 TRANSFAC - 73662705 73662717 2.0E-06 CAAAAGTAAAAAT 13 V_GLI_Q2_M01037 TRANSFAC - 73662651 73662662 6.0E-06 TGTGGGAGGTCC 12 V_SP1_Q2_01_M00933 TRANSFAC + 73660923 73660932 4.0E-06 CCCCGCCCCC 10 V_MEF2A_05_M01301 TRANSFAC + 73658549 73658560 3.0E-06 ACCTATTTTAAG 12 V_SP1_Q4_01_M00932 TRANSFAC + 73658527 73658539 6.0E-06 GGGGGGAGGGGCT 13 V_SP1_Q4_01_M00932 TRANSFAC - 73660921 73660933 3.0E-06 CGGGGGCGGGGCG 13 V_STAT1_Q6_M01823 TRANSFAC + 73661881 73661890 6.0E-06 TTCGAGGAAA 10 V_STAT1_Q6_M01823 TRANSFAC + 73666190 73666199 1.0E-06 TTCCGGGAAA 10 V_BHLHB2_04_M02845 TRANSFAC + 73666249 73666271 3.0E-06 CACAGCTACACATGGATGGAGGC 23 V_NR2F2_04_M02887 TRANSFAC - 73659453 73659468 3.0E-06 AGCTCCGGGTCATTCA 16 V_PAX4_04_M00380 TRANSFAC - 73664524 73664553 1.0E-05 AGCAAATAAGCTTCCAGAATTTCCCATCCC 30

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